In the mid-1800s, Lionel Smith Beale, an English physician and microscopist at King’s College in London, peered through his microscope at a smear of saliva and mucus coughed up by a man with cancer of ...

Zhang and his colleagues designed a generative AI model called ChromoGen to quickly ‘read’ DNA sequences and predict the ...

Northwestern Medicine scientists have discovered new details about how the human genome produces instructions for creating ...

Storage of eukaryotic DNA in small, compact nuclei requires that this DNA be tightly coiled and compacted in the form of chromatin. However, the structure of chromatin also appears to serve a ...

Chromatin is a mixture of DNA and proteins that form the chromosomes found in the cells of humans. The study found that a ...

When genes are coiled and compacted into chromatin, they're no longer accessible to transcription factors. So how does the cell know where to uncoil in a process called chromatin remodeling?

A novel, freely available AI tool has cut the time it takes to determine chromatin structure from days to minutes. The 3D ...

A generative AI-based technique can predict thousands of 3D genomic structures in just minutes, enabling researchers to more ...

Inside the cell nucleus, DNA and proteins form a complex called chromatin, which has several levels of organization, allowing cells to cram two meters of DNA into a nucleus that is only one ...