The scientists found that within an hour of infection, HSV-1 co-opts two genes — RNA polymerase II (RNAP 2) and DNA topoisomerase (TOP1) — that compact the host’s chromatin into super-dense bundles.

A team of scientists at the MRC Laboratory of Medical Sciences (LMS) has uncovered a previously unknown mechanism that ...

Histone tails and their epigenetic modifications play crucial roles in gene expression regulation by altering the architecture of chromatin. However, the structural mechanisms by which histone tails ...

The ChIA-PET analysis revealed chromatin interactions, including those between the promoter and superenhancer regions, but it remained unclear to what extent superenhancers represent a sum of ...

Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, ...

Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, ...

A UNIGE team has identified two new proteins that regulate gene expression, a discovery that could pave the way for new cancer and brain disorder treatments.