Ceramide metabolism has garnered increasing attention in liver diseases, but its role in cholestatic liver injury remains unclear. Here the authors show that targeting ACER3, a ceramidase ...

Bile duct inflammation and scarring, known as cholangiopathies, can disrupt bile flow, leading to liver damage and ...

The length of your entire digestive system from the mouth to the anus is approximately 30 feet long. Your digestive system is responsible for breaking down the foods you eat so that you can absorb ...

Atlanta Falcons quarterback Kirk Cousins met with owner Arthur Blank on Wednesday and the team doesn't intend to release him, NFL Network Insider Tom Pelissero reported Friday, per sources.

The former Falcons starting quarterback requested and received a meeting with team owner Arthur Blank on Wednesday, during which he said he wants a move to a team where he can be the starter ...

2Dr. Li Dak-Sum Research Centre, the University of Hong Kong, Hong Kong 3Department of Surgery, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong 4Department of Surgery, ...

A urinary tract infection is any microbial invasion that results in an inflammatory response in the epithelium of the urinary tract. Bladder instillation of gentamicin is safe and effective in ...

Background: Immune checkpoint blockade (ICB)-based immunotherapy has inspired new hope for advanced biliary tract cancer (BTC) treatment; however, there are no prior studies that primarily focus on ...

Background: Anti-programmed cell death protein 1 and its ligand (anti-PD1/PDL1) have been proposed as a promising therapeutic option for advanced biliary tract cancer (aBTC). Given the scarce ...