New research sheds light on how ketamine affects the brain by targeting a specific NMDA receptor subtype, GluN1-2B-2D.

Ketamine has received a Hollywood makeover. It used to be known as a rave drug (street name special K) and cat anesthetic. However, in recent years, some doctors have prescribed ketamine to treat ...

We often think about diseases in terms of the symptoms they present. A cold might give you the sniffles or even GI distress, while malaria can give you fever, chills, or nausea, for example. These ...

Newer antipsychotics, such as clozapine, olanzapine, risperidone, quetiapine and ziprasidone, have a different receptor-binding profile, interacting with both D and 5-HT receptors; they less ...

In September 2024, a new antipsychotic drug to ease positive ... Cobenfy, however, targets a different family of receptors in the brain, known as muscarinic receptors. Clinical trials have ...

Distinct pharmacologic profiles, especially actions on 5-hydroxytryptamine (5-HT) receptor subtypes, may contribute to the advantage of atypical antipsychotics in terms of adverse effects.

School of Information Science and Technology, ShanghaiTech University, 393 Middle Huaxia Road, Pudong New Area, Shanghai 201210, China Shanghai Institute for Advanced Immunochemical Studies, ...