The immune system responds to an infection by producing antibodies that recognize and bind to the cell surface of the ...

"This strategy is known as antigenic variation," explains physicist Maria Colomé-Tatché, who is Professor of Functional Genomics and Cell Biology at LMU's Biomedical Center and leader of the ...

Each year, the virus mutates slightly in a process called antigenic drift. The greater the mutation, the less likely that your immune system will recognize and fight back against the disease.

Usually such mutations are minor, resulting in a process called antigenic drift. Even minor changes in the virus’s make-up, however, mean that new vaccines must be developed to combat it.

In response to pathogens, vaccines, and other antigenic stimuli, BCR and TCR repertoires undergo changes through clonal expansion, somatic mutation, and selective reshaping of immune cell populations.

Catani and colleagues provide data on antigenic properties of neuraminidase proteins of pandemic H1N1 and show that antigenic diversity of the neuraminidase from 2009 to 2020 largely falls into two ...