At the current average wholesale cost of the smaller, commercially available alteplase vial (containing 50 mg), the average cost per milligram of alteplase is $27.50. [27] With the use of current ...

Three 100-mg vials of alteplase injection a were reconstituted with sterile water b to yield solutions of 0.5, 1, and 2 mg/mL. A transfer adapter c was used to draw 1-mL samples into 5- mL plastic ...