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Gut13d
Tumour-intrinsic alterations and stromal matrix remodelling promote Wnt-niche independence during diffuse-type gastric cancer progression
Background Development of diffuse-type gastric cancer (DGC) starts with intramucosal lesions that are primarily composed of ...
gut.bmj4d
Perspective on enhancing CRC risk prediction
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gut.bmj11d
Response to: correspondence on 'Revisiting the role of sphincterotomy in sphincter of Oddi disorder: a critical appraisal of the RESPOnD study by Zeng
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gut.bmj18h
O33 Health call-a novel system to improve patient pre-assessment
Introduction Newcastle upon Tyne NHS Foundation Trust Endoscopy Pre-Assessment is a high volume service currently pre-assesing 900 patients per month. A large waiting list for procedures bulit up as a ...
gut.bmj4d
Gut microbiome analysis as a tool towards targeted non-invasive biomarkers for early hepatocellular carcinoma
Objective To characterise gut microbiome in patients with hepatocellular carcinoma (HCC) and evaluate the potential of microbiome as non-invasive biomarkers for HCC. Design We collected 486 faecal ...
gut.bmj2d
Guidelines for the management of iron deficiency anaemia
Correspondence to Brian B Scott, Department of Medicine, Lincoln County Hospital, Lincoln LN2 5QY, UK; drbbscott{at}aol.com Iron deficiency anaemia (IDA) occurs in 2–5% of adult men and postmenopausal ...
gut.bmj6d
Dissecting transcriptional heterogeneity in primary gastric adenocarcinoma by single cell RNA sequencing
Objective Tumour heterogeneity represents a major obstacle to accurate diagnosis and treatment in gastric adenocarcinoma (GA). Here, we report a systematic transcriptional atlas to delineate molecular ...
gut.bmj9d
Low-coverage whole genome sequencing of low-grade dysplasia strongly predicts advanced neoplasia risk in ulcerative colitis
Background The risk of developing advanced neoplasia (AN; colorectal cancer and/or high-grade dysplasia) in ulcerative colitis (UC) patients with a low-grade dysplasia (LGD) lesion is variable and ...
gut.bmj3d
YAP1 mediates gastric adenocarcinoma peritoneal metastases that are attenuated by YAP1 inhibition
Correspondence to Shumei Song, Departmental of GI Medical Oncology, U.T.MD. Anderson Cancer Center, Houston, TX 77030, USA; ssong{at}mdanderson.org; Jaffer A Ajani ...
gut.bmj6d
Niche-specific functional heterogeneity of intestinal resident macrophages
Correspondence to Professor Guy Boeckxstaens, Translational Research in Gastrointestinal Disorders (TARGID), Department of Chronic Diseases, Metabolism and Ageing (Chrometa), KU Leuven, Leuven, ...
gut.bmj4d
Accuracy of a no-biopsy approach for the diagnosis of coeliac disease across different adult cohorts
Objective We aimed to determine the predictive capacity and diagnostic yield of a 10-fold increase in serum IgA antitissue transglutaminase (tTG) antibody levels for detecting small intestinal injury ...
gut.bmj6d
Safely restarting GI endoscopy in the era of COVID-19
Correspondence to Dr Bu"Hussain Hayee, King"s Health Partners Institute for Therapeutic Endoscopy, King"s College Hospital, London SE5 9RS, UK; b.hayee{at}nhs.net The COVID-19 pandemic has placed ...