The overlap in the functions of Blimp-1 and XBP-1 was restricted to that response, with Blimp-1 uniquely regulating activity of the kinase mTOR and the size of plasma cells.

To prove plasma cells were directly or indirectly limiting TFH cell function, the scientists employed knock-out mouse technology, models lacking the ability to produce a certain protein.

Our cells carry out hundreds of thousands of important functions every day, all of which are carefully orchestrated at a ...

pH balance: Substances present in blood plasma act as buffers, allowing plasma to maintain a pH within normal ranges, which helps to support cell function. Transportation: Plasma in the blood ...

Immunoglobulins are molecules plasma cells produce following B-cell activation due to ... et al. (2019). Antibody structure and function: The basis for engineering therapeutics. https://www.ncbi ...

Multiple myeloma is a form of blood cancer that affects the plasma cells. In some cases, plasma cells gradually decline and cause a condition called hypogammaglobulinemia. Medical News Today ...

Normal plasma cells function to make antibodies, helping the body to fight infection. Myeloma involves malignant plasma cells that build up in the bone marrow or the soft tissue in the center of ...

Plasma cells are B cell descendants that have become fully specialized. They have matured into machines whose sole purpose is to churn out antibodies of a specific design. Several different drugs are ...

Find out what you need to know about platelet-rich plasma treatment, and discover the risks and benefits, ... are a type of blood cell. Their main function is clotting blood.