Toxic megacolon is a rare but reported presentation of severe pseudomembranous colitis. This article reviews the reported cases of Clostridium difficile with toxic megacolon in the literature and ...

The finding of small-bowel distension on X-ray (so-called impending megacolon) identifies patients at high risk of developing toxic megacolon Ciclosporin or infliximab can be used in patients with ...

Unstable cardiovascular status in acute hemorrhage. Severe ulcerative colitis. Toxic megacolon complicating ulcerative colitis. Myasthenia gravis. Ileostomy or colostomy. Autonomic neuropathy.

Bleeding GI ulcer. Active inflammatory or infectious colitis that can lead to toxic megacolon. Toxic megacolon. Myasthenia gravis. Discontinue if incomplete mechanical intestinal obstruction is ...