As scientists, we often think we understand a virus—its structure, its tricks, the way it moves through the body. But every ...

SARS-CoV-2, the virus responsible for COVID-19, infects cells by binding its spike protein to angiotensin-converting enzyme 2 (ACE2) receptors. Blocking this interaction with inhibitors could prevent ...

Small-molecule inhibitors targeting viral proteins could serve as an effective alternative for controlling the spread of COVID-19 at both individual and community levels. In this vein, a recent study ...

It's been five years since COVID-19 was declared a global pandemic. As SARS-CoV-2 shifts to endemic status, questions about ...

A SARS-CoV-2 antibody, NT-108, exhibits potent therapeutic effects in vivo. Cryo-EM structure of the spike complexed with single-chain Fv of NT108 reveals its neutralizing mechanism, providing ...

A Stanford-led team has found two antibodies that can work together to defeat all SARS-CoV-2 variants ... This area, within the Spike N-terminal domain, or NTD, had been overlooked because ...

TIME ELAPSED: 6–11 DAYS The Virus Takes Countermeasures SARS-CoV-2 uses several tactics to thwart the immune system’s response. Tactic 1: The virus spike may camouflage itself with sugar ...

The new virus, emerging in Wuhan, China, is called SARS-CoV-2 and is responsible for the disease known as ... their vaccine development on a segment of the SARS-CoV or MERS-CoV spike protein (a ...