SARS-CoV-2, the virus responsible for COVID-19, infects cells by binding its spike protein to angiotensin-converting enzyme 2 ...

Binding is the first step for infection, and several mutations in previous variants of concern have been shown to be important for increasing the spike's binding to human ACE2. “We simulated the ...

However, mutations in the spike protein can alter its structure, reducing the effectiveness ... has developed COVID-19 eliminative Short Peptide Inhibiting ACE2 binding (CeSPIACE), a mutation ...