SARS-CoV-2, the virus responsible for COVID-19 ... However, mutations in the spike protein can alter its structure, reducing the effectiveness of these inhibitors. In a significant breakthrough, ...

It's been five years since COVID-19 was declared a global pandemic. As SARS-CoV-2 shifts to endemic status, questions about ...

A phylogenetic tree of SARS-CoV-2 sequences, built with Nextstrain, displays sequences colored by their clade and organized by collection date. Over time, sequences mutate and diverge, forming new ...

The COVID-19 pandemic highlighted the urgent need for effective therapeutic agents against SARS-CoV-2. Although vaccines ...

A biophysical map of viral fitness The key player in SARS-CoV-2's infection process is the receptor binding domain (RBD) of the spike protein.

Small-molecule inhibitors targeting viral proteins could serve as an effective alternative for controlling the spread of COVID-19 at both individual and community levels. In this vein, a recent study ...

Viruses like SARS-CoV-2 use sugar molecules to hide from the immune system, but scientists at Scripps Research have designed ...

Efforts to contain the spread of SARS-CoV-2 may benefit from a new analytical tool developed by a team led by biologists at Boston College, who report their computer simulation of molecular ...

CoV-2, a new merbecovirus found in bats across China, that utilises the ACE2 receptor for cellular entry—raising concerns ...

For all the mysteries that remain about the novel coronavirus and the COVID-19 disease it causes, scientists have generated an incredible amount of fine-grained knowledge in a surprisingly short time.

As the United States enters its fourth month of response to the COVID-19 crisis, many are pointing to the testing of people potentially infected with the disease as the key to effective mitigation of ...