An easy method for efficiently identifying proteins that interact with bioactive molecules has been developed by chemical biologists at RIKEN. This innovation, published in ChemBioChem, could help to ...

Proteins are the infinitely varied chemicals that make cells work, and science has a pretty good idea how they are made. But a critical aspect underlying the machinery of protein manufacture has long ...

A comprehensive review of the discovery and molecular dissection of the eukaryotic ribosome-associated quality-control pathway for degradation of nascent proteins arising from interrupted translation.

A ribosome is composed of two subunits: large and small. During translation, ribosomal subunits assemble together like a sandwich on the strand of mRNA, where they proceed to attract tRNA ...

A new method for studying ribosome function UIC scientists use native chemical ligation to fuse peptides to tRNAs Date: November 1, 2022 Source: University of Illinois Chicago ...

When ribosomes go rogue Unusual variations in the cellular protein factory can skew development, help cancer spread, and more. But ribosome variety may also play biological roles, scientists say.

The ribosome has two subunits, each made up of RNA and proteins. It interacts with a host of other molecules to guide the assembly of new proteins.

"The ribosome has a masterful design: a few bit flips of its sequence transform its repertoire of motions, enabling it decode genetic information with even higher fidelity, ...

“We wanted to know how quickly a human ribosome can read the genetic code, how quickly it finds the tRNA that’s complementary to the mRNA,” explained said co-first author Mikael Holm, PhD.

A ribosome itself is a "huge complex of messenger RNA and 50 proteins. Most things in cells are complexes of RNA and proteins." Such simulations are increasing dramatically in sophistication.

The ribosome is the machine that translates the DNA code into the proteins that are essential for life. Virtually every molecule made in every living cell was made either by the ribosome or by enzymes ...