Despite being so widespread, the common cold has consistently eluded effective medical treatment, both because of the vast number of viruses that cause it—more than 150 strains of rhinovirus infect ...

“We’ve known for 50 years that [rhinovirus] replicated better in the nose, but the mechanism has never been clearly defined,” study coauthor Akiko Iwasaki of Yale told BBC News. In mice, as it turns ...

Assembly and budding of a virus from a membrane microdomain. Viruses have an outer protein shell called a capsid which surrounds the viral nucleic acid. Enveloped viruses, such as HIV, have an ...

Even the most common among those, rhinovirus, has more than a hundred different strains. "Curing" a cold would actually mean eradicating a long list of respiratory viruses that happen to cause ...

The HIV-1 capsid (pink) cracks the rings of the nuclear pore complex (orange, green and blue rings) as it traverses the channel. Credit: Philipp Kreysing Using state-of-the-art cellular tomography ...

A research team has successfully utilized human respiratory organoids (mini-organs) to propagate human rhinovirus C (HRV-C), which had previously been refractory to conventional virus cultivation.

Lower capsid doses further facilitate successful manufacturing and reduce the cost of goods. “If you say to a patient with a devastating CNS disease, ‘There’s a therapeutic that could save ...