How proteins guide plasma cells to bone marrow for long-term immunity
Vaccine effectiveness relies on creating a strong antibody response that can be reactivated to fight future infections. Now, ...
The Scientist1y
Alcohol Leaves its Mark on Immune Cells
The team isolated bone marrow cells from the animals after one year of heavy drinking and evaluated monocytes and stem cells for gene expression, cytokine production, and epigenetic changes that ...
Nature2mon
Active movement of T cells away from a chemokine
There was selective repulsion of subpopulations of T cells at high concentrations of recombinant SDF-1 or naturally occurring bone marrow-derived ... and challenge of mice. C57 BL/6J mice (Jackson ...
Nature13y
Use of immunoglobulins in the prevention of GvHD in a xenogeneic NOD/SCID/γc− mouse model
Using a xenogeneic model of GvHD in NOD/SCID/γc− (NSG) mice, we showed that weekly administration of IVIG significantly reduced the incidence and associated mortality of GvHD to a degree ...