Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

The ex vivo cartilage defect model was prepared from cartilage harvested from the KRS patients’ excised knee joints. Only cartilage from the mid-region of the lateral-femoral compartment ...

Stromal cell therapy is a promising frontier in lupus research, especially for people whose lupus doesn’t respond to other treatments (called refractory lupus). We were the first lupus organization in ...

December 2024, immediately following the approval of the world's first mesenchymal stromal cells clinical trial, the U.S. FDA ...

Introduction Ligament and tendon are prone to degeneration through ageing and injury and current therapies are largely ineffective. The identification of a cell population within tendon with stem cell ...

Researcher suggests compounds secreted by high-risk MSCs that are detectable in the bloodstream could act as biomarkers for ...

Vimentin is a type III intermediate filament (IF) protein normally expressed in cells that develop into connective tissue, blood vessels, and lymphatic tissue (mesenchymal cells). Despite being ...

(A) The infection of Ad-Shh in MSCs (fluorescence microscope, × 100). (B) Validation of the expression of Shh by Ad-Shh in MSCs (Western blot). (C, D) The effects of Shh on BMP9-induced ALP ...

Xintela's interim analysis of data from the knee osteoarthritis clinical study shows safety and positive efficacy results, 18 months after treatment with XSTEM. The results demonstrate statistically s ...