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When the COVID-19 pandemic swept across the world in 2020, the mRNA vaccines came to the rescue of many people—but in the ...
Penn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal "recipe" for ionizable lipids—key ingredients in lipid nanoparticles (LNPs), the molecules behind the ...
The global lipid nanoparticles (LNP) contract development and manufacturing organization (CDMO) market is poised for ...
Fragile mRNA molecules used in COVID-19 vaccines can’t get into cells on their own. They owe their success to lipid nanoparticles that took decades to refine ...
Researchers have cooked up a new way to improve mRNA delivery, developing an optimal “recipe” for ionizable lipids — key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 ...
When COVID-19 struck, lipid nanoparticles met the immediate challenge—now they’re overcoming barriers to global deployment of mRNA vaccines of all kinds.
Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the central nervous system. Nature Materials , 2025; DOI: 10.1038/s41563-024-02114-5 Cite This Page : ...
A study in the Journal of the American Chemical Society reports steps toward making inhalable mRNA medicines a possibility. Researchers outline their improved lipid-polymer nanoparticle for ...
The researchers packaged mRNA instructions for firefly luciferase - a bioluminescent protein often used in research - into lipid nanoparticles, and then injected them into mice either ...
Blood–brain-barrier-crossing lipid nanoparticles (BLNPs) effectively and safely deliver mRNA to the brain via systemic administration. [Created with BioRender.com in the lab of Yizhou Dong, PhD ...
Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge ...