or that seasonal influenza vaccines have some protective value. So far, sequencing of H5N1 viruses from US cases has shown no changes in the HA gene associated with increased infectiousness or ...

Only influenza A viruses infect nonhuman hosts, and a reassortment of genes can occur between those ... and are the reservoir from which new HA subtypes are introduced into humans (Palese, 2004).

The influenza A virus genome consists of eight segments of single-stranded, negative-sense viral RNA, which encode multiple proteins, including hemagglutinin (HA), neuraminidase (NA), matrix ...

To maintain vaccine efficacy, WHO regularly updates influenza vaccine strains based on global epidemiological, virological, ...

Variations in the HA and NA genes determine the subtype and strain. It is possible to sequence the entire viral genome of influenza via reverse transcription of all eight RNA segments. Gene ...

Selective gene silencing technologies such as RNA interference (RNAi) and nucleic acid enzymes have shown therapeutic potential for treating viral infections. Influenza virus is one of the major ...

CPSF30: 30-kDa cleavage and polyadenylation specificity factor; F2: Frame 2; HA ... over 300 antiviral genes that ultimately lead to suppression of virus propagation. Influenza virus antagonism ...