Chronic hepatitis B virus (HBV) infection continues to pose a major global health threat. The virus evades immune responses and antiviral therapies due to the persistence of covalently closed circular ...

Hepatitis B virus infections can progress from an acute ... % base pairing to form an unbranched rod-like structure. The genome sequence shows no homology to the 3300-nucleotide genome of a ...

Scientists discovered a way to block hepatitis B infection using an anticancer drug, offering hope for new treatments.

So how, then, do researchers determine the sequence of A's, G's, C's, and T's that comprise the genome? The answer is that they've had to develop a new process, what Bruce Birren of MIT's ...

Seroconversion from HBeAg to anti-HBe is usually associated with serum HBV DNA undetectable by hybridization technology and remission of liver disease. Nevertheless, a certain proportion of anti ...

The US joins Moldova, Hong Kong, and New Zealand as countries to greenlight the company's Phase I trial of PBGENE-HBV.

However, I was fascinated to discover that viruses like hepatitis B hijack epigenetic mechanisms, even using human DNA-packaging proteins to regulate their activity.” Not long after, study first ...

How did it become possible to sequence the 3 billion base pairs in the human genome? More than a quarter of a century’s worth of work from hundreds of scientists made such projects possible.

Hepatitis B virus (HBV) is the leading cause of cirrhosis, hepatocellular carcinoma, and liver-related death globally.1,2 The highest prevalence is found in low-income and middle-income countries ...