The presence and the positioning of nucleosomes on DNA can be important in directing cellular mechanisms to transcribe some genes. "We found that to be the case for the HBV gene encoding protein X—the ...

Early in infection, HBV establishes an independent “minichromosome” consisting of the viral covalently closed circular DNA (cccDNA) genome and host histones. But as the authors noted ...

Worldwide, hepatitis B is thought to be the second deadliest infection; about 5% of the global population are infection and it can lead to liver cancer. | Microbiology ...

Hepatitis B virus (HBV) is the leading cause of cirrhosis, hepatocellular carcinoma, and liver-related death globally.1,2 The highest prevalence is found in low-income and middle-income countries ...

Occult HBV infection is defined by the existence of HBV DNA in serum, lymphoid cells (PBMC) and/or the liver and virus-genome replicative intermediates (i.e., covalently closed circular DNA ...

Chances are you've seen an illustration of DNA's double-helix structure and even pictures of the chromosomes that make up the human genome. But where and how does the famous double helix fit into ...

PBGENE-HBV, which comprises an ARCUS-encoding ... to cause expression/add function), elimination (removing a genome e.g. viral DNA or mutant mitochondrial DNA), and excision (removing a large ...

Atomic force microscopy images show hepatitis B DNA in its natural state ... The Risca Lab studies the 3D architecture of the genome and how the packaging of DNA helps to control the transcription ...