Methotrexate is an antimetabolite that ... and competing with folic acid in cancer cells, resulting in folic acid deficiency and cell death. Normal cells are not spared; thus, significant side ...

Methotrexate is thought to act via folate-pathway enzymes; however, studies seeking associations between patient responses to methotrexate and single nucleotide polymorphisms (SNPs) in folate ...

B vitamins serve a range of important functions in the body: They help you form new blood cells and maintain cellular health, promote metabolism (the conversion of food into energy), and ...

Methotrexate 1g/vial ... Infection. Dehydration. Folate deficiency. Ascites, pleural effusions: evacuate fluid, monitor for toxicity and reduce dose or discontinue if needed.