Beyond the ladder-like structure described above, another key characteristic of double-stranded DNA is its unique three-dimensional shape. The first photographic evidence of this shape was ...

Scientists at EMBL have captured how human chromosomes fold into their signature rod shape during cell division, using a ...

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves.

For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process ...

Chances are you've seen an illustration of DNA's double-helix structure and even pictures of the chromosomes that make up the human genome. But where and how does the famous double helix fit into ...

But James Watson and Francis Crick's claim was a valid one, for they had in fact discovered the structure of DNA, the chemical that encodes instructions for building and replicating almost all ...

Scientists have uncovered evidence that modern humans emerged from two long-separated ancestral groups, not just one. This ...

Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.

Earlier that morning, in the nearby Cavendish laboratory, the two scientists had discovered the structure of deoxyribonucleic acid, or DNA. This discovery changed the world of science and medicine ...

In the new work, Rothemund and his colleagues used DNA origami to create a lilypad-like structure—a flat, circular surface about 100 nanometers in diameter, tethered by a DNA linker to a gold ...

By unveiling Pol-theta's DNA-bound structure—its active state—the study provides a blueprint for designing more effective cancer drugs. "We now have a much clearer picture of how Pol-theta ...

Those short, added pieces of DNA fold the scaffold and give it shape, acting as "staples" that hold the structure together. The technique can then be used to create shapes ranging from a map of ...