For the first time, scientists have captured the exact moment DNA begins to unravel, shedding light on a fundamental chemical process that enables DNA to serve as the blueprint for life. A recent ...

MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.

Original DNA template - DNA is a double helix made of two complementary strands. Each strand can be used as a template to create a new DNA molecule. Free DNA nucleotides – needed to form the new ...

Watson and Crick's discovery of DNA structure in 1953 revealed a possible mechanism for DNA replication. So why didn't Meselson and Stahl finally explain this mechanism until 1958 ...

The study of DNA replication started almost as soon as the structure of DNA was elucidated, and it continues to this day. Currently, the stages of initiation, unwinding, primer synthesis ...

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For ...

DNA is a complex molecule that consists of two strands coiled around each other to form a double helix structure. Comparison of a single ... functioning and survival of all living organisms. DNA ...

But James Watson and Francis Crick's claim was a valid one, for they had in fact discovered the structure of DNA, the chemical that encodes instructions for building and replicating almost all ...

We employ fully reconstituted yeast and human DNA replication systems to investigate the structure and biochemical mechanism of the eukaryotic replication machinery. A particular focus of the lab is ...

When organisms encounter problems -- what scientists call "replication stress ... bases (represented by G in the DNA code) can fold into a DNA structure called a G-quadruplex, or G4 for ...