(5) Chemicals cleave the oligonucleotide and remove protecting groups. (6) Continued exposure to harsh chemicals damages the DNA and reduces yields. Scientists use short oligonucleotides as primers ...

Here's how it worked: Data, 0 or 1, was represented by a short piece of single-stranded DNA, called an oligonucleotide, that contained a series of bases: adenine, thymine, guanine and cytosine.

Korro Bio's OPERA platform offers precise RNA editing for genetic diseases like Alpha-1 antitrypsin deficiency. Learn more on ...

Wave Life Sciences’ Phase II open-label trial investigating its disease-modifying drug for boys living with Duchenne Muscular ...

Standard schematic of oligonucleotide activities in pathogenesis disease progression. Decoys bind to transcription factors of targeted DNA at the earliest phase. Subsequently, antisense RNA, small ...

Notable oligonucleotide synthesis companies such ... Future synthesis, Integrated DNA Technologies, Kaneka Eurogentec, LGC Biosearch Technologies, Microsynth, Nitto Avecia, Ribo Biotechnology ...

Single-cell transcriptomics has revolutionized the study of cellular diversity and function by enabling gene expression ...

Oligonucleotides are short sequences of DNA that can modulate or control gene expression. In this way, they have the potential to address the underlying causes of various diseases such as heart ...

Rolling-circle amplification (RCA) driven by DNA polymerase can replicate circularized oligonucleotide probes with either linear or geometric kinetics under isothermal conditions. In the presence ...

Oligonucleotide therapeutics are becoming increasingly popular, with scientists developing treatments for rare diseases, cancer, and respiratory disorders. To ensure their quality, researchers must ...

LCGC International spoke with Daniel Meston and Dwight Stoll from Gustavus Adolphus College in St. Peter, Minnesota, USA, ...