Alan Herbert, explores the understanding of genome information storage, and the significance of repetitive sequences called ...
DNA (deoxyribonucleic acid ... Artificial nucleic acids with a fixed conformation of the backbone of the oligonucleotide can form stable duplexes, however, the synthesis of modified nucleotides ...
Furthermore, she learned that DNA molecules were in a helical conformation. She also noticed that when DNA fibers experienced humidity at 75%, they appeared long and thin, but when they were drier ...
Together, his work established that DNA bound to cGAS directly, changed its conformation, and generated cGAMP to, in turn, prod STING to trigger type I IFN production and elicit an innate immune ...