ACE2 protein sequence conservation has therefore been evaluated across species, and species with amino acid substitutions in ACE2 were ranked low for susceptibility to SARS-CoV-2 infection.
This protein is found on the surface of SARS-CoV-2 (the virus responsible for COVID-19), it binds to angiotensin-converting enzyme 2 (ACE2 ... to modify the DNA sequence of the spike protein ...