Cooper Flagg and the NBA prospect-laden Duke Blue Devils are the main attraction of the East Region, but this is also where we could see a few games that end up closer than expected -- and maybe even a couple upsets.

Cooper Flagg's health is the biggest storyline in the East Region as top-seeded Duke awaits the return of its freshman sensation. The Blue Devils beat North Carolina and Louisville in the ACC Tournament without the ACC Player of the Year,

The Blue Devils have the easiest route to the Final Four in San Antonio, Texas, according to the betting market.