SportsLine's model revealed its college basketball predictions for Arizona Wildcats vs. Cooper Flagg and the Duke Blue Devils on Thursday in the Sweet 16 of the 2025 NCAA Tournament

The No. 1-seeded Duke Blue Devils and No. 4-seeded Arizona Wildcats square off on Thursday night in a can’t-miss Sweet 16 showdown. Duke has advanced through the first two rounds of the tournament with ease, outscoring Mount St. Mary’s 93-49 in the first round and conquering Baylor 89-66 in the second round.

Duke’s first two NCAA tournaments under Jon Scheyer ended prematurely in winnable games. This Blue Devils roster was built upon the lessons inherent in those “hard truths.”

UNC matchup on Friday will be the first in the NCAA tournament between the rivals. "Really great for the sport," Tar Heels coach Courtney Banghart said.

North Carolina coach Courtney Banghart and fifth-year senior Alyssa Ustby, Duke coach Kara Lawson and Ashlon Jackson address the Tar Heels and Blue Devils’ upcoming Sweet 16 matchup in Birmingham.